Manchester United have been drawn to face Real Sociedad in the Europa League round of 16, while Tottenham Hotspur will take on AZ Alkmaar.
Elsewhere, Rangers will face Jose Mourinho’s Fenerbahce, AS Roma go up against Athletic Club and Ajax drew Eintracht Frankfurt.
United last faced the Spanish side in 2022 in a pair of Europa League group-stage games. They also met in the knockout stages the year prior, with United winning 4-0 on aggregrate.
The winner of that tie will face either Lyon or FCSB in the semifinals.
Meanwhile, Spurs will be familiar to their opponents, Dutch side AZ. The two sides have already met once this season iin the group phase — that game ended with Spurs winning 1-0.
A semifinal tie with either Ajax or Frankfurt will await the winner.
Europa League round-of-16 draw:
Real Sociedad v Manchester United
AZ Alkmaar vs. Tottenham Hotspur
Viktoria Plzen vs. Lazio
Bodo/Glimt vs. Olympiacos
Ajax Amsterdam vs.Eintracht Frankfurt
AS Roma vs. Athletic Club
Fenerbahce vs. Rangers
FCSB vs. Lyon