St Kilda will look to remain undefeated and claim its biggest scalp yet when it takes on Collingwood in a Gather Round blockbuster at the Adelaide Oval.
The Pies (3-1, 122.3%) are looking to respond after their first loss of the season, during which they conceded 10 unanswered goals to the Brisbane Lions after entering the round as premiership favourites.
St Kilda (4-0, 160.4%) has thrived under new coach Ross Lyon and is looking to win five straight matches to start the season.
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Aliir Aliir produces save of the season! | 00:33
This match gets underway at 4:50pm from Adelaide Oval.
Watch it live on Fox Footy (channel 504) from 4pm.
Follow Collingwood v St Kilda in our live blog below!